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CS-W001157 4
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(6-bromo-1H-benzo[d]imidazol-2-yl)methanol

  • CAS No. 540516-28-7

  • Cat. No. CS-W000761
  • Molecule weight227.06
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(6-bromo-1H-benzo[d]imidazol-2-yl)methanol|CS-W000761

Structure of 540516-28-7

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General Information

  • CAS No. 540516-28-7
  • Cat. No. CS-W000761
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇BrN₂O
  • Molecular Weight 227.06
  • Synonym(s) 5-Bromobenzimidazole-2-methanol
  • SMILES OCc1nc2ccc(Br)cc2[nH]1

Description

This bench-stable benzimidazole derivative features a brominated heterocyclic core paired with a reactive alcohol handle. The pendant hydroxymethyl group enables straightforward functionalization, while the bromine substituent supports downstream cross-coupling transformations. This compound serves as a key building block for bioactive molecule synthesis and materials development.

Application

(5-Bromo-1H-benzo[d]imidazol-2-yl)methanol serves as a versatile building block for the synthesis of biologically relevant heterocycles, enabling efficient functionalization at the benzoimidazole core. Its pendant aldehyde functionality facilitates nucleophilic additions, reductive amination, and coupling reactions with minimal side reactivity. The molecule exhibits excellent bench stability and is readily purified by standard chromatographic methods, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   48.91
  • LogP   1.8177
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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