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CS-W001157 4
Total: USD 88.00

2-Bromobenzo[b]thiophene

  • CAS No. 5394-13-8

  • Cat. No. CS-W005319
  • Purity≥95%
  • MDL No.MFCD08435846

*For research and further manufacturing use only, not for direct human use.

2-Bromobenzo[b]thiophene|CS-W005319

Structure of 5394-13-8

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General Information

  • CAS No. 5394-13-8
  • Cat. No. CS-W005319
  • Purity ≥95%
  • MDL No. MFCD08435846
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrS
  • Molecular Weight 213.09
  • Synonym(s) Benzo(b)thiophene, 2-bromo-
  • SMILES BrC1=CC2=C(S1)C=CC=C2

Description

2-Bromobenzo[b]thiophene serves as a key heterocyclic building block in the synthesis of advanced organic materials and pharmaceutical intermediates. This brominated fused ring system combines enhanced stability with predictable reactivity, enabling efficient coupling reactions under standard conditions. The thiophene core provides electron-rich character, while the bromine substituent facilitates palladium-catalyzed cross-coupling transformations.

Synthesis

  • Route1

    References

    • BASF AKTIENGESELLSCHAFT Patent: WO2006/56418 A2, 2006 ; Location in patent: Page/Page column 68-69 ;
  • Route2
    • null|null
      1191415-24-3
    • ~89%
    • In-stock
      2-Bromobenzo[b]thiophene|CS-W005319
      5394-13-8

    References

    • Ji, Yong; Li, Pinhua; Zhang, Xiuli; Wang, Lei Organic and Biomolecular Chemistry, 2013 , vol. 11, # 24 p. 4095 - 4101
  • Route3
    • null|null
      67-56-1
    • null|null
      201230-82-2
    • null|null
      1191415-24-3
    • ~8%
    • In-stock
      2-Bromobenzo[b]thiophene|CS-W005319
      5394-13-8
    • In-stock
      Methyl benzo[b]thiophene-2-carboxylate|CS-0043114
      22913-24-2

    References

    • Organic Letters, , vol. 13, # 11 p. 2868 - 2871

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319-H413
Precautionary Statements : P264-P270-P273-P280-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.6638
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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