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CS-W001157 4
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1-(1,1-Dimethylethyl) hydrogen N-(1-oxohexadecyl)-L-glutamate

  • CAS No. 536721-25-2

  • Cat. No. CS-0539841
  • Purity≥98%
  • MDL No.MFCD30489507

*For research and further manufacturing use only, not for direct human use.

1-(1,1-Dimethylethyl) hydrogen N-(1-oxohexadecyl)-L-glutamate|CS-0539841

Structure of 536721-25-2

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General Information

  • CAS No. 536721-25-2
  • Cat. No. CS-0539841
  • Purity ≥98%
  • MDL No. MFCD30489507
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₄₇NO₅
  • Molecular Weight 441.64
  • Synonym(s) L-Glutamic acid, N-(1-oxohexadecyl)-, 1-(1,1-dimethylethyl) ester
  • SMILES O=C(O)CC[C@@H](C(OC(C)(C)C)=O)NC(CCCCCCCCCCCCCCC)=O

Description

This amphiphilic glutamate derivative integrates a hydrophobic hexadecanoyl tail with a sterically shielded tert-butyl group and a polar head, enabling stable dispersion in aqueous media. It functions as a tunable surfactant for lipid-based delivery systems and membrane mimicry studies.

Application

This compound serves as a functionalized amino acid derivative with a tert-butyl-protected amine and a long-chain acyl group, enabling controlled peptide coupling and surfactant-like properties. Its stability under standard synthetic conditions and orthogonal protection profile facilitate use in complex molecule assembly, particularly in amphiphilic peptide scaffolds and membrane-active compound development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   95.53
  • LogP   4.8243
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   19

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