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CS-W001157 4
Total: USD 88.00

4-Morpholinopiperidine

  • CAS No. 53617-35-9

  • Cat. No. CS-W008934
  • Purity≥97%
  • MDL No.MFCD03274733

*For research and further manufacturing use only, not for direct human use.

4-Morpholinopiperidine|CS-W008934

Structure of 53617-35-9

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General Information

  • CAS No. 53617-35-9
  • Cat. No. CS-W008934
  • Purity ≥97%
  • MDL No. MFCD03274733
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₈N₂O
  • Molecular Weight 170.25
  • Synonym(s) 4-(Piperidin-4-yl)morpholine
  • SMILES N1(CCOCC1)C2CCNCC2

Application

4-Morpholinopiperidine serves as a versatile nitrogen-containing heterocyclic building block in medicinal chemistry, enabling the construction of diverse pharmacologically active scaffolds. Its amine functionality facilitates salt formation and conjugation, while the morpholine ring imparts favorable solubility and metabolic stability. The compound exhibits bench stability and compatibility with standard coupling reactions, making it a practical choice for late-stage functionalization and lead optimization workflows.

Synthesis

  • Route1
    • null|null
      415967-79-2
    • ~91%
    • In-stock
      4-Morpholinopiperidine|CS-W008934
      53617-35-9

    References

    • Huchler, Guenther; Rall, Werner; Ries, Uwe Patent: US2008/45705 A1, 2008 ; Location in patent: Page/Page column 10-11 ;
  • Route2
    • null|null
      110-91-8
    • null|null
      79099-07-3
    • ~%
    • In-stock
      4-Morpholinopiperidine|CS-W008934
      53617-35-9

    References

    • US2005/239843 A1, ; Page/Page column 15 ;
  • Route3
    • null|null
      110-91-8
    • null|null
      67-63-0
    • null|null
      29976-53-2
    • ~%
    • In-stock
      4-Morpholinopiperidine|CS-W008934
      53617-35-9

    References

    • US2003/203909 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   24.5
  • LogP   0.0706
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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