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CS-W001157 4
Total: USD 88.00

4-Aminobenzohydrazide

  • CAS No. 5351-17-7

  • Cat. No. CS-0012956
  • Purity≥96%
  • MDL No.MFCD00007606

*For research and further manufacturing use only, not for direct human use.

4-Aminobenzohydrazide|CS-0012956

Structure of 5351-17-7

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General Information

  • CAS No. 5351-17-7
  • Cat. No. CS-0012956
  • Purity ≥96%
  • MDL No. MFCD00007606
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉N₃O
  • Molecular Weight None
  • Synonym(s) p-Aminobenzohydrazide; p-Aminobenzoic acid hydrazide
  • SMILES O=C(NN)C1=CC=C(N)C=C1

Description

BrettPhos Pd G4 is an N-substituted 2-aminobiphenylpalladium methanesulfonate precatalyst. It is a fourth generation (G4) Buchwald precatalyst that is similar to the third generation (G3) precatalysts except that the amino group on the biphenyl backbone is methylated. This modification helps to prevent the limitations of using the third generation precatalysts. It is air, moisture and thermally-stable and shows good solubility in common organic solvents. BrettPhos Pd G4 is highly useful in cross-coupling reactions. Some of its excellent features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.

Synthesis

  • Route1

    References

    • Albatal, Mona; Ghani, Mohamad Abdul; El-Faham, Ayman; Al-Hazimi, Hassan M.; Hammud, Hassan H. Journal of the Korean Chemical Society, 2010 , vol. 54, # 4 p. 419 - 428
  • Route2

    References

    • Soliman; Darwish Journal of Medicinal Chemistry, 1983 , vol. 26, # 11 p. 1659 - 1663
  • Route3
    • 4-Aminobenzoic acid Conivaptan Impurity|CS-0213989
      150-13-0
    • ~%
    • In-stock
      4-Aminobenzohydrazide|CS-0012956
      5351-17-7

    References

    • Journal of Pharmacy and Pharmacology, , vol. 53, # 2 p. 267 - 272

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352-P304+P340

Quality Control

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Computational Chemistry Data

  • TPSA   81.14
  • LogP   -0.1277
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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