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CS-W001157 4
Total: USD 88.00

N-Propylacetamide

  • CAS No. 5331-48-6

  • Cat. No. CS-0246738
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N-Propylacetamide|CS-0246738

Structure of 5331-48-6

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General Information

  • CAS No. 5331-48-6
  • Cat. No. CS-0246738
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO
  • Molecular Weight 101.15
  • Synonym(s) N-(n-Propyl)Acetamide
  • SMILES CCCNC(C)=O

Description

N-Propylacetamide features a polar amide functional group flanked by alkyl chains, offering enhanced solubility in organic solvents while maintaining thermal stability. This structure enables efficient integration into synthetic intermediates for pharmaceutical and agrochemical applications under standard conditions.

Application

N-Propylacetamide serves as a versatile amide building block in synthetic organic chemistry, enabling selective functionalization and serving as a stable precursor in peptide-like scaffolds. Its moderate polarity facilitates purification by chromatography, while the propyl group enhances lipophilicity for medicinal chemistry applications. The amide functionality exhibits robust stability under standard reaction conditions, supporting compatibility with diverse transformations including nucleophilic acyl substitutions and catalytic reductions.

Synthesis

  • Route1
    • null|null
      623-40-5
    • ~%
    • In-stock
      N-Propylacetamide|CS-0246738
      5331-48-6

    References

    • Tetrahedron Letters, , vol. 52, # 38 p. 4888 - 4891
  • Route2
    • null|null
      64-19-7
    • null|null
      108-03-2
    • ~58%
    • In-stock
      N-Propylacetamide|CS-0246738
      5331-48-6

    References

    • Watanabe, Yoshihisa; Tsuji, Yasushi; Kondo, Teruyuki; Takeuchi, Ryo Journal of Organic Chemistry, 1984 , vol. 49, # 23 p. 4451 - 4455
  • Route3
    • null|null
      107-10-8
    • null|null
      75-36-5
    • ~%
    • In-stock
      N-Propylacetamide|CS-0246738
      5331-48-6

    References

    • Journal of the American Chemical Society, , vol. 59, p. 2003

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   0.5325
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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