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CS-W001157 4
Total: USD 88.00

3-Ethyl-1h-indole

  • CAS No. 1484-19-1

  • Cat. No. CS-0234454
  • Purity≥98%
  • MDL No.MFCD01881367

*For research and further manufacturing use only, not for direct human use.

3-Ethyl-1h-indole|CS-0234454

Structure of 1484-19-1

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General Information

  • CAS No. 1484-19-1
  • Cat. No. CS-0234454
  • Purity ≥98%
  • MDL No. MFCD01881367
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁N
  • Molecular Weight None
  • Synonym(s) None
  • SMILES CCC1=CNC2=CC=CC=C12

Description

3-Ethyl-1H-indole features a sterically accessible indole core with enhanced solubility and stability compared to unsubstituted analogs. This derivative integrates readily into bioactive scaffolds, enabling efficient access to functionalized heterocycles in medicinal chemistry and materials science applications.

Application

3-Ethyl-1H-indole serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, offering a stable, bench-ready scaffold for C3 functionalization. Its electron-rich indole core facilitates electrophilic substitution and transition-metal-catalyzed coupling reactions, while the alkyl substituent enhances solubility and metabolic stability. Functions effectively in the construction of bioactive molecules and pharmaceutical intermediates.

Synthesis

  • Route1

    References

    • Guyon, Carole; Baron, Marc; Lemaire, Marc; Popowycz, Florence; Metay, Estelle Tetrahedron, 2014 , vol. 70, # 12 p. 2088 - 2095
  • Route2
    • null|null
      577968-42-4
    • ~88%
    • In-stock
      3-Ethyl-1h-indole|CS-0234454
      1484-19-1

    References

    • Banwell, Martin G.; Kelly, Brian D.; Kokas, Okanya J.; Lupton, David W. Organic Letters, 2003 , vol. 5, # 14 p. 2497 - 2500
  • Route3

    References

    • Linciano, Pasquale; Pizzetti, Marianna; Porcheddu, Andrea; Taddei, Maurizio Synlett, 2013 , vol. 24, # 17 p. 2249 - 2254

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   15.79
  • LogP   2.7303
  • H_Acceptors   0
  • H_Donors   1
  • Rotatable_Bonds   1

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