N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-benzyl-L-cysteine

Name: N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-benzyl-L-cysteine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 53298-33-2
Cat. No. CS-0101069
Purity≥98%
MDL No.MFCD00065633

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-benzyl-L-cysteine|CS-0101069

Structure of 53298-33-2

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General Information

CAS No. 53298-33-2
Cat. No. CS-0101069
Purity ≥98%
MDL No. MFCD00065633
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₅H₂₃NO₄S
Molecular Weight 433.52
Synonym(s) None
SMILES O=C(O)[C@H](CSCC1=CC=CC=C1)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Description

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-benzyl-L-cysteine is a protected cysteine derivative featuring a fluorenylmethoxycarbonyl (Fmoc) group for orthogonal side-chain protection. The S-benzyl moiety stabilizes the thiol during peptide synthesis, enabling selective deprotection and efficient coupling under standard conditions. This bifunctional design supports high-yield assembly of complex sequences in solid-phase peptide synthesis workflows.

Synthesis

Route1
- In-stock
  
  3054-01-1
- In-stock
  
  88744-04-1
- ~97%
- In-stock
  
  53298-33-2
References
- Schoen, Istvan; Kisfaludy, Lajos Synthesis, 1986 , # 4 p. 303 - 305
Route2
- In-stock
  
  3054-01-1
- ~89%
- In-stock
  
  53298-33-2
References
- Kisfaludy, Lajos; Schoen, Istvan Synthesis, 1983 , # 4 p. 325 - 327

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 75.63
LogP 4.9117
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 8

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Cysteine and derivatives

Building Blocks Functional Group Fmoc

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Key Words

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N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-benzyl-L-cysteine

CAS No. 53298-33-2

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