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Structure of 53269-35-5
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3-Formyl-1H-indole-4-carbonitrile features a strategically positioned aldehyde and nitrile group on the indole scaffold, enabling direct functionalization in transition-metal-catalyzed couplings and multicomponent reactions. This electron-deficient heterocycle serves as a key building block for bioactive molecule synthesis, particularly in medicinal chemistry and materials science.
3-Formyl-1H-indole-4-carbonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to indole-based scaffolds through classic C–H functionalization and transition-metal-catalyzed coupling reactions. The ortho-functionalized structure supports sequential transformations, with the formyl group amenable to reductive amination, condensation, or oxidation, while the nitrile offers a handle for hydrolysis or cycloaddition. Bench-stable and readily purified by recrystallization, it facilitates scalable synthesis of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: