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Structure of 69047-36-5
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1-Methyl-1H-indole-7-carbaldehyde features a benzene-fused indole core with a methyl group at the 1-position and an aldehyde function at the 7-position, enabling direct coupling in cross-coupling reactions. The electron-rich indole scaffold enhances reactivity in transition-metal-catalyzed transformations, while the aldehyde moiety provides a handle for derivatization via imine formation or reduction. This compound serves as a key building block in the synthesis of bioactive heterocycles and functionalized pharmaceutical intermediates.
1-Methyl-1H-indole-7-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to indole-based scaffolds through standard functional group transformations. Its aldehyde functionality facilitates reductive amination, Grignard additions, and coupling reactions, while the methylated indole core enhances metabolic stability and solubility. Bench-stable and readily purified by flash chromatography, it functions effectively in multi-step syntheses of kinase inhibitors and CNS-targeted compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: