Lot numbers can be found on the outside label of a product:
2-Hydrazinyl-6-methylpyridine
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CAS No. 5315-24-2
- Cat. No. CS-W021701
- Purity≥95%
- MDL No.MFCD07786311
*For research and further manufacturing use only, not for direct human use.
Structure of 5315-24-2
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General Information
- CAS No. 5315-24-2
- Cat. No. CS-W021701
- Purity ≥95%
- MDL No. MFCD07786311
- Storage -20°C, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₆H₉N₃
- Molecular Weight 123.16
- Synonym(s) 2-METHYL-6-HYDRAZINOPYRIDINE
- SMILES N(N)C1=NC(=CC=C1)C
Description
2-Hydrazinyl-6-methylpyridine features a reactive hydrazino group appended to a methyl-substituted pyridine scaffold, enabling direct incorporation into heterocyclic architectures. This bench-stable derivative facilitates efficient coupling reactions and serves as a key intermediate in the synthesis of bioactive nitrogen-rich compounds.
Application
2-Hydrazinyl-6-methylpyridine serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyridazine and triazine scaffolds via condensation and cyclization reactions. Its hydrazinyl group exhibits high reactivity toward carbonyl compounds and electrophiles, facilitating rapid construction of nitrogen-rich frameworks under mild conditions. The methyl substituent enhances solubility and modulates electronic properties, contributing to improved bench stability and ease of purification in synthetic workflows.
Synthesis
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Route1
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In-stock
18368-63-3 - ~62%
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In-stock
5315-24-2
References
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Uchikawa, Osamu; Mitsui, Keita; Asakawa, Akiko; Morimoto, Shigeru; Yamamoto, Masataka; Kimura, Hiroyuki; Moriya, Takeo; Mizuno, Masahiro Patent: US2003/187014 A1, 2003 ;
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Route2
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In-stock
38557-71-0 - ~69%
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In-stock
5315-24-2
References
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Nitlikar, Lakshmikant H.; Darandale, Sunil N.; Shinde, Devanand B. Letters in Organic Chemistry, 2013 , vol. 10, # 5 p. 348 - 352
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Route3
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In-stock
407-22-7 - ~%
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In-stock
5315-24-2
References
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US2008/90861 A1, ; Page/Page column 16 ;
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Safety Information
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 50.94
- LogP 0.67562
- H_Acceptors 3
- H_Donors 2
- Rotatable_Bonds 1
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Key Words
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