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CS-W001157 4
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Bromo-PEG2-C2-azide

  • CAS No. 530151-56-5

  • Cat. No. CS-0108237
  • Purity≥97%
  • MDL No.MFCD25424115

*For research and further manufacturing use only, not for direct human use.

Bromo-PEG2-C2-azide|CS-0108237

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General Information

  • CAS No. 530151-56-5
  • Cat. No. CS-0108237
  • Purity ≥97%
  • MDL No. MFCD25424115
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂BrN₃O₂
  • Molecular Weight 238.08
  • Synonym(s) None
  • SMILES BrCCOCCOCCN=[N+]=[N-]

Description

Bromo-PEG2-C2-azide features a reactive bromo group flanked by a short PEG2 spacer and a terminal azide, enabling efficient bioconjugation. This bifunctional reagent integrates seamlessly into click chemistry workflows, offering precise site-specific labeling under standard conditions.

Application

Bromo-PEG2-C2-azide serves as a versatile bifunctional linker for conjugation and macrocyclic scaffold assembly. The terminal azide group enables efficient copper-catalyzed (CuAAC) or strain-promoted (SPAAC) click reactions, while the bromoethyl terminus facilitates nucleophilic substitution with amines or thiols. This PEG2-spaced architecture provides enhanced solubility and reduced aggregation, making it ideal for synthesizing bioconjugates, peptide-drug hybrids, and functionalized polymers with predictable, high-yielding transformations under standard bench conditions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   67.22
  • LogP   1.7248
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   8

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