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CS-W001157 4
Total: USD 88.00

Bromo-PEG3-azide

  • CAS No. 1446282-43-4

  • Cat. No. CS-0114338
  • Molecule weight282.13
  • Purity≥97%
  • MDL No.MFCD25424113

*For research and further manufacturing use only, not for direct human use.

Bromo-PEG3-azide|CS-0114338

Structure of 1446282-43-4

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General Information

  • CAS No. 1446282-43-4
  • Cat. No. CS-0114338
  • Purity ≥97%
  • MDL No. MFCD25424113
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆BrN₃O₃
  • Molecular Weight 282.13
  • Synonym(s) None
  • SMILES BrCCOCCOCCOCCN=[N+]=[N-]

Description

Bromo-PEG3-azide is a bifunctional reagent featuring a reactive bromo group and a terminal azide, enabling site-specific conjugation in bioorthogonal chemistry. This PEG3 spacer provides enhanced solubility and reduced aggregation, while the azide moiety facilitates efficient copper-catalyzed or strain-promoted cycloaddition reactions. Designed for modular synthesis in drug delivery and probe development.

Application

Bromo-PEG3-azide serves as a versatile bifunctional linker for bioconjugation and polymer functionalization. The bromo group enables efficient coupling with nucleophilic sites such as amines or thiols, while the terminal azide supports reliable copper-catalyzed (CuAAC) or strain-promoted (SPAAC) cycloadditions. Its three-ethylene glycol spacer provides excellent solubility and reduced non-specific binding, enhancing performance in aqueous environments. This reagent offers robust stability under standard bench conditions and facilitates clean purification, making it ideal for synthesizing conjugates, probes, and functionalized materials in medicinal chemistry and materials science workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   76.45
  • LogP   1.7414
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   11

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