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1-(4-Bromophenyl)imidazolidin-2-one

  • CAS No. 530081-14-2

  • Cat. No. CS-0149704
  • Purity≥98%
  • MDL No.MFCD08444010

*For research and further manufacturing use only, not for direct human use.

1-(4-Bromophenyl)imidazolidin-2-one|CS-0149704

Structure of 530081-14-2

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General Information

  • CAS No. 530081-14-2
  • Cat. No. CS-0149704
  • Purity ≥98%
  • MDL No. MFCD08444010
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉BrN₂O
  • Molecular Weight 241.08
  • Synonym(s) 1-(4-Bromophenyl)tetrahydro-2H-imidazol-2-one
  • SMILES O=C1NCCN1C2=CC=C(Br)C=C2

Description

1-(4-Bromophenyl)imidazolidin-2-one features a brominated aromatic ring fused to a rigid imidazolidin-2-one core, delivering enhanced stability and targeted reactivity. This bench-stable scaffold integrates readily into medicinal chemistry libraries, enabling efficient access to bioactive compounds through direct functionalization at the bromo site.

Application

1-(4-Bromophenyl)imidazolidin-2-one serves as a versatile building block in medicinal chemistry, enabling the synthesis of imidazolidinone-based scaffolds via standard functional group transformations. The bromo substituent facilitates palladium-catalyzed cross-coupling reactions, while the imidazolidinone core provides structural rigidity and hydrogen-bonding capability. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step syntheses requiring orthogonal reactivity and compatibility with diverse reaction conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   32.34
  • LogP   1.9787
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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