Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(3,4-Dihydro-2H-pyran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

  • CAS No. 1046811-99-7

  • Cat. No. CS-0055079
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(3,4-Dihydro-2H-pyran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0055079

Structure of 1046811-99-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1046811-99-7
  • Cat. No. CS-0055079
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉BO₃
  • Molecular Weight 210.08
  • Synonym(s) 3,4-Dihydro-2H-pyran-5-ylboronic acid, pinacol ester
  • SMILES CC1(C)C(C)(C)OB(C2=COCCC2)O1

Description

This boronate ester features a dihydropyran-5-yl moiety integrated into a stable tetramethyl-1,3,2-dioxaborolane scaffold. It serves as a bench-stable, moisture-tolerant building block for Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under standard conditions.

Application

This boronate ester serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The dihydropyran-5-yl group provides a stable, bench-compatible scaffold with excellent functional group tolerance and compatibility with standard reaction protocols. Its tetramethyl-substituted dioxaborolane ring enhances stability and facilitates purification, making it ideal for iterative synthesis and complex molecule assembly in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • null|null
      1227068-77-0
    • In-stock
      Bis(pinacolato)diborane|CS-D1216
      73183-34-3
    • ~%
    • In-stock
      2-(3,4-Dihydro-2H-pyran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0055079
      1046811-99-7

    References

    • WO2010/57121 A1, ; Page/Page column 142 ; WO 2010/057121 A1
  • Route2

    References

    • Chemistry Letters, , vol. 37, # 6 p. 664 - 665
  • Route3
    • null|null
      110-87-2
    • null|null
      25015-63-8
    • ~%
    • In-stock
      2-(3,4-Dihydro-2H-pyran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0055079
      1046811-99-7
    • In-stock
      2-(3,4-Dihydro-2H-pyran-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0097347
      1025707-93-0

    References

    • Bulletin of the Chemical Society of Japan, , vol. 81, # 12 p. 1535 - 1553

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   27.69
  • LogP   2.3121
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1046811-99-7 sigma1046811-99-7 manufacturer1046811-99-7 price1046811-99-7 structure1046811-99-7 SDSbuy 1046811-99-71046811-99-7 supplier1046811-99-7 uses1046811-99-7 molecular weightprice of 1046811-99-71046811-99-7 chemical name formula of 1046811-99-7
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label