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CS-W001157 4
Total: USD 88.00

2-Amino-4-(hydroxymethyl)phenol

  • CAS No. 52820-13-0

  • Cat. No. CS-0197260
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Amino-4-(hydroxymethyl)phenol|CS-0197260

Structure of 52820-13-0

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General Information

  • CAS No. 52820-13-0
  • Cat. No. CS-0197260
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉NO₂
  • Molecular Weight 139.15
  • Synonym(s) 2-amino-4-hydroxymethylphenol
  • SMILES OC1=CC=C(C=C1N)CO

Description

2-Amino-4-(hydroxymethyl)phenol features a strategically positioned hydroxymethyl group adjacent to an electron-rich aromatic ring, enabling direct functionalization in synthetic pathways. This bench-stable phenolic scaffold integrates readily into bioactive molecule design, offering enhanced solubility and reactivity under standard conditions.

Application

2-Amino-4-(hydroxymethyl)phenol serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and functionalized aromatic scaffolds. Its ortho-amino and benzylic hydroxyl groups offer complementary reactivity for coupling, oxidation, and protection strategies. The compound exhibits good bench stability and facilitates efficient derivatization under mild conditions, making it well-suited for iterative synthesis workflows in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   66.48
  • LogP   0.4667
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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