Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4,6-Dimethoxypyrimidine

  • CAS No. 5270-94-0

  • Cat. No. CS-W016467
  • Purity≥97%
  • MDL No.MFCD00955844

*For research and further manufacturing use only, not for direct human use.

4,6-Dimethoxypyrimidine|CS-W016467

Structure of 5270-94-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 5270-94-0
  • Cat. No. CS-W016467
  • Purity ≥97%
  • MDL No. MFCD00955844
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O₂
  • Molecular Weight 140.14
  • Synonym(s) 4,6-dimethoxypyrimidin
  • SMILES COC1=CC(OC)=NC=N1

Description

4,6-Dimethoxypyrimidine serves as a key heterocyclic scaffold in medicinal chemistry, offering enhanced solubility and metabolic stability. The ortho-dimethoxy substitution pattern enables selective functionalization at C5, facilitating the synthesis of advanced intermediates for kinase inhibitors and antiviral agents. This bench-stable compound integrates readily into multistep sequences under mild conditions.

Application

4,6-Dimethoxypyrimidine serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling efficient construction of heterocyclic scaffolds. Its ortho-dimethoxy substitution pattern enhances reactivity in nucleophilic displacement and transition-metal-catalyzed coupling reactions. The compound exhibits excellent bench stability, facilitates straightforward purification, and demonstrates broad functional group tolerance, making it ideal for iterative synthesis workflows and API development.

Synthesis

  • Route1
    • In-stock
      4,6-Dichloropyrimidine|CS-W018513
      1193-21-1
    • null|null
      124-41-4
    • ~%
    • In-stock
      4,6-Dimethoxypyrimidine|CS-W016467
      5270-94-0

    References

    • Wu, Gang; Mikkilineni, Amarendra B.; Sher, Philip M.; Murugesan, Natesan; Gu, Zhengxiang Patent: US2006/287341 A1, 2006 ; Location in patent: Page/Page column 41 ; US 20060287341 A1
  • Route2
    • In-stock
      2-Chloro-4,6-dimethoxypyrimidine|CS-W017478
      13223-25-1
    • ~18%
    • Ethyl 4,6-dimethoxypyrimidine-2-carboxylate|CS-0318631
      128276-49-3
    • In-stock
      4,6-Dimethoxypyrimidine|CS-W016467
      5270-94-0

    References

    • Bessard, Yves; Crettaz, Roger Tetrahedron, 1999 , vol. 55, # 2 p. 405 - 412

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   44.24
  • LogP   0.4938
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4,6-Dimethoxypyrimidine sigma4,6-Dimethoxypyrimidine manufacturer4,6-Dimethoxypyrimidine price4,6-Dimethoxypyrimidine structure4,6-Dimethoxypyrimidine SDSbuy 4,6-Dimethoxypyrimidine4,6-Dimethoxypyrimidine supplier4,6-Dimethoxypyrimidine uses4,6-Dimethoxypyrimidine molecular weightprice of 4,6-Dimethoxypyrimidine4,6-Dimethoxypyrimidine chemical name formula of 4,6-Dimethoxypyrimidine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label