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Structure of 52088-10-5
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3-Iodo-1-methyl-1H-indazole is a heterocyclic iodide featuring a methylated indazole core with a reactive iodine at the 3-position. This substitution pattern enables facile cross-coupling reactions, making it a valuable scaffold for constructing complex pharmaceutical intermediates and bioactive molecules under standard conditions.
3-Iodo-1-methyl-1H-indazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biologically relevant indazole scaffolds. The iodide group provides high reactivity in Suzuki, Stille, and Negishi couplings, while the methylated indazole core offers enhanced metabolic stability and favorable pharmacokinetic properties. Its bench-stable nature and ease of purification make it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: