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CS-W001157 4
Total: USD 88.00

Indazole

  • CAS No. 271-44-3

  • Cat. No. CS-W008689
  • Purity≥97%
  • MDL No.MFCD00005691

*For research and further manufacturing use only, not for direct human use.

Indazole|CS-W008689

Structure of 271-44-3

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General Information

  • CAS No. 271-44-3
  • Cat. No. CS-W008689
  • Purity ≥97%
  • MDL No. MFCD00005691
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆N₂
  • Molecular Weight None
  • Synonym(s) None
  • SMILES C12=CC=CC=C1NN=C2

Description

Tos-PEG4-methyl ester is a PEG linker with tosyl and methyl ester moieties. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG linker increases the water solubility of the compound. Methyl ester can be hydrolyzed under strong basic condition.

Synthesis

  • Route1

    References

    • DALHOUSIE UNIVERSITY; LUNDGREN, Rylan, J.; STRADIOTTO, Mark Patent: WO2012/68335 A2, 2012 ; Location in patent: Page/Page column 60-61 ;
  • Route2

    References

    • Piramed Limited; Genentech, Inc. Patent: US2008/76758 A1, 2008 ; Location in patent: Page/Page column 75 ; US 20080076758 A1
  • Route3
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      Indazole|CS-W008689
      271-44-3

    References

    • Jin, Tienan; Yang, Fan; Yamamoto, Yoshinori Collection of Czechoslovak Chemical Communications, 2009 , vol. 74, # 6 p. 957 - 972

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   1.5629
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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