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CS-W001157 4
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3-Iodo-1H-indazole

  • CAS No. 66607-27-0

  • Cat. No. CS-W003212
  • Purity≥95%
  • MDL No.MFCD04972469

*For research and further manufacturing use only, not for direct human use.

3-Iodo-1H-indazole|CS-W003212

Structure of 66607-27-0

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General Information

  • CAS No. 66607-27-0
  • Cat. No. CS-W003212
  • Purity ≥95%
  • MDL No. MFCD04972469
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅IN₂
  • Molecular Weight 244.03
  • Synonym(s) 3-Iodoindazole
  • SMILES IC1=NNC2=C1C=CC=C2

Description

3-Iodo-1H-indazole is a bench-stable heterocyclic iodide featuring a reactive iodine atom at the 3-position, enabling direct coupling in cross-coupling reactions. The electron-deficient indazole core facilitates efficient functionalization, while its solubility profile supports use in diverse synthetic workflows.

Application

3-Iodo-1H-indazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. The iodide group provides high reactivity under standard conditions, facilitating efficient C–C bond formation with aryl, heteroaryl, and alkenyl partners. Its stability under ambient conditions and compatibility with diverse functional groups make it well-suited for iterative synthesis of complex heterocyclic scaffolds and API intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.1675
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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