(R)-2-Methyl-1-phenylpropan-1-amine hydrochloride

Name: (R)-2-Methyl-1-phenylpropan-1-amine hydrochloride
Brand: ChemScene
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CAS No. 51600-25-0
Cat. No. CS-0154339
Purity≥97%
MDL No.MFCD12068520

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-2-Methyl-1-phenylpropan-1-amine hydrochloride|CS-0154339

Structure of 51600-25-0

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Description

(R)-2-Methyl-1-phenylpropan-1-amine hydrochloride is a chiral amine scaffold featuring a stereogenic center at the alpha carbon, enabling precise asymmetric synthesis. The phenyl group imparts rigidity and π-conjugation, while the protonated amine ensures high solubility in aqueous media. This salt form enhances stability and facilitates handling under standard bench conditions.

Application

(R)-2-Methyl-1-phenylpropan-1-amine hydrochloride serves as a chiral building block for asymmetric synthesis, enabling the construction of stereodefined biaryl and heterocyclic scaffolds. Its bench-stable hydrochloride salt facilitates handling and purification, while the pendant amine group supports diverse functionalization via nucleophilic substitution or reductive amination. This enantiopure scaffold is routinely employed in medicinal chemistry campaigns targeting CNS-active compounds and kinase inhibitors.

General Information

CAS No. 51600-25-0
Cat. No. CS-0154339
Purity ≥97%
MDL No. MFCD12068520
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₆ClN
Molecular Weight 185.69
Synonym(s) (1R)-2-methyl-1-phenylpropan-1-amine,hydrochloride
SMILES CC(C)[C@H](C1=CC=CC=C1)N.Cl

Computational Chemistry Data

TPSA 26.02
LogP 2.7642
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

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(R)-2-Methyl-1-phenylpropan-1-amine hydrochloride

CAS No. 51600-25-0

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