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CS-W001157 4
Total: USD 88.00

4-Isobutyloxazolidine-2,5-dione

  • CAS No. 51248-35-2

  • Cat. No. CS-0317706
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Isobutyloxazolidine-2,5-dione|CS-0317706

Structure of 51248-35-2

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General Information

  • CAS No. 51248-35-2
  • Cat. No. CS-0317706
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁NO₃
  • Molecular Weight 157.17
  • Synonym(s) (+/-)-4-isobutyl-oxazolidine-2,5-dione
  • SMILES CC(CC1C(OC(N1)=O)=O)C

Description

4-Isobutyloxazolidine-2,5-dione features a sterically hindered oxazolidinedione core that enhances stability and facilitates selective reactivity in synthetic transformations. This bench-stable scaffold integrates readily into complex molecular architectures, offering a reliable platform for constructing nitrogen-containing heterocycles under standard conditions.

Application

4-Isobutyloxazolidine-2,5-dione serves as a stable, bench-friendly synthon for the introduction of isobutyl groups in asymmetric synthesis. Its oxazolidinone core enables predictable diastereoselective transformations, particularly in nucleophilic additions and enolate chemistry. The molecule functions effectively as a chiral auxiliary or building block in peptide and heterocyclic scaffold construction, offering excellent functional group tolerance and straightforward purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.4
  • LogP   0.6675
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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