Lot numbers can be found on the outside label of a product:
L-Leucine NCA
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CAS No. 3190-70-3
- Cat. No. CS-0031376
- Purity≥97%
- MDL No.MFCD03411292
*For research and further manufacturing use only, not for direct human use.
Structure of 3190-70-3
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General Information
- CAS No. 3190-70-3
- Cat. No. CS-0031376
- Purity ≥97%
- MDL No. MFCD03411292
- Storage -20°C, sealed storage, away from moisture
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₇H₁₁NO₃
- Molecular Weight 157.17
- Synonym(s) N-Carboxyanhydride L-leucine; N-Carboxyleucine anhydride; NSC 351903; (S)-4-isobutyloxazolidine-2,5-dione
- SMILES CC(C)C[C@H](N1)C(OC1=O)=O
Description
L-Leucine NCA delivers a reactive, side-chain-functionalized monomer for precision polymer synthesis. This bench-stable derivative integrates seamlessly into polypeptide architectures via ring-opening polymerization, enabling controlled access to bioactive materials with tailored hydrophobicity and structural integrity.
Application
L-Leucine NCA serves as a robust monomer for the synthesis of polypeptides via ring-opening polymerization, offering high reactivity and controlled chain growth. Its well-defined structure enables precise incorporation into biodegradable polyamides, with excellent functional group tolerance and bench stability. Ideal for preparing sequence-defined polymers in medicinal chemistry and materials science applications.
Synthesis
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Route1
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75-44-5 -
61-90-5 - ~83%
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In-stock
3190-70-3
References
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Gerlach, Arne; Geller, Thomas Advanced Synthesis and Catalysis, 2004 , vol. 346, # 9-10 p. 1247 - 1249
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Route2
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61-90-5
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503-38-8
- ~89%
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In-stock
3190-70-3
References
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Milo, Anat; Neumann, Ronny Advanced Synthesis and Catalysis, 2010 , vol. 352, # 13 p. 2159 - 2165
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Route3
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61-90-5
- ~78%
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In-stock
3190-70-3
References
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Bioresearch, Inc. Patent: US5028693 A1, 1991 ;
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 55.4
- LogP 0.6675
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 2
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Key Words
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