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CS-W001157 4
Total: USD 88.00

5-(Chloromethyl)oxazolidin-2-one

  • CAS No. 22625-57-6

  • Cat. No. CS-W011062
  • Purity≥97%
  • MDL No.MFCD00005269

*For research and further manufacturing use only, not for direct human use.

5-(Chloromethyl)oxazolidin-2-one|CS-W011062

Structure of 22625-57-6

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General Information

  • CAS No. 22625-57-6
  • Cat. No. CS-W011062
  • Purity ≥97%
  • MDL No. MFCD00005269
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆ClNO₂
  • Molecular Weight 135.55
  • Synonym(s) 5-Chloromethyl-2-oxazolidinone
  • SMILES O=C1OC(CCl)CN1

Description

5-(Chloromethyl)oxazolidin-2-one is a reactive heterocyclic intermediate featuring a chloromethyl group at the 5-position, enabling efficient functionalization. This bench-stable, moisture-tolerant compound integrates readily into synthetic sequences requiring site-specific alkylation or conjugation.

Synthesis

  • Route1
    • null|null
      590-28-3
    • null|null
      106-89-8
    • ~71%
    • In-stock
      5-(Chloromethyl)oxazolidin-2-one|CS-W011062
      22625-57-6

    References

    • Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 51, # 9 p. 1430 - 1435
  • Route2
    • null|null
      106-89-8
    • ~36%
    • In-stock
      5-(Chloromethyl)oxazolidin-2-one|CS-W011062
      22625-57-6

    References

    • US5162354 A1, ;
  • Route3
    • 3-(3-Chloro-2-hydroxypropyl)thiazolidine-2,4-dione|CS-0266376
      141037-39-0
    • ~41%
    • In-stock
      5-(Chloromethyl)oxazolidin-2-one|CS-W011062
      22625-57-6

    References

    • Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 27, # 8 p. 915 - 917 Khimiya Geterotsiklicheskikh Soedinenii, , # 8 p. 1137 - 1140

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   0.3336
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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