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CS-W001157 4
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Thiazol-4-ylmethanamine hydrochloride

  • CAS No. 117043-86-4

  • Cat. No. CS-0038080
  • Purity≥96%
  • MDL No.MFCD06738774

*For research and further manufacturing use only, not for direct human use.

Thiazol-4-ylmethanamine hydrochloride|CS-0038080

Structure of 117043-86-4

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General Information

  • CAS No. 117043-86-4
  • Cat. No. CS-0038080
  • Purity ≥96%
  • MDL No. MFCD06738774
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇ClN₂S
  • Molecular Weight 150.63
  • Synonym(s) Thiazole-4-methylamine hydrochloride
  • SMILES NCC1=CSC=N1.Cl

Description

Thiazol-4-ylmethanamine hydrochloride features a thiazole ring bearing a primary amine group at the 4-position, delivering a potent nucleophilic handle for conjugation. This bench-stable derivative integrates readily into bioconjugation workflows and serves as a key building block in medicinal chemistry, particularly for targeted drug delivery systems and kinase inhibitor scaffolds.

Application

Thiazol-4-ylmethanamine hydrochloride serves as a versatile building block for medicinal chemistry and catalytic synthesis. The thiazole scaffold provides robust metabolic stability and favorable pharmacokinetic properties, while the primary amine functionality enables straightforward derivatization via amide coupling, alkylation, or reductive amination. Its crystalline solid form ensures ease of handling and purification, with excellent bench stability under ambient conditions. This compound functions as a key intermediate in the construction of heterocyclic APIs and bioactive molecules.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.0236
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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