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CS-W001157 4
Total: USD 88.00

2-Amino-2-methylpropanenitrile hydrochloride

  • CAS No. 50846-36-1

  • Cat. No. CS-W005215
  • Purity≥95%
  • MDL No.MFCD08456816
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Amino-2-methylpropanenitrile hydrochloride|CS-W005215

Structure of 50846-36-1

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Description

2-Amino-2-methylpropanenitrile hydrochloride features a sterically hindered tertiary amine and nitrile functionality, enabling robust coupling reactions under mild conditions. This bench-stable salt delivers high reactivity in nucleophilic additions and serves as a key intermediate in the synthesis of bioactive heterocycles and amino acid analogs.

Application

2-Amino-2-methylpropanenitrile hydrochloride serves as a stable, bench-ready building block for the synthesis of nitrile-containing heterocycles and amino acid derivatives. Its functional group tolerance enables straightforward incorporation into diverse synthetic sequences, including cyclization reactions and nucleophilic substitutions. The hydrochloride salt enhances solubility and handling, facilitating purification and scalability in medicinal chemistry and process development workflows.

General Information

  • CAS No. 50846-36-1
  • Cat. No. CS-W005215
  • Purity ≥95%
  • MDL No. MFCD08456816
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉ClN₂
  • Molecular Weight 120.58
  • Synonym(s) alpha-aminoisobutyronitrile hydrochloride
  • SMILES CC(C)(N)C#N.[H]Cl

Computational Chemistry Data

  • TPSA   49.81
  • LogP   0.66908
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group :
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

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