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Structure of 508235-16-3
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This boronate reagent features a 2,3-difluoro-4-methylphenyl scaffold, offering enhanced stability and selective coupling efficiency in Suzuki-Miyaura reactions. The electron-deficient aryl ring enables rapid transmetalation, while the methyl group provides steric modulation for improved reaction control. Bench-stable under standard conditions, it facilitates reliable synthesis of fluorinated biaryl architectures.
2,3-Difluoro-4-methylphenylboronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. Its ortho-fluorine substituents enhance stability and modulate reactivity, while the methyl group provides a handle for further functionalization. The boronic acid moiety offers excellent bench stability, predictable coupling efficiency, and compatibility with diverse reaction partners, making it well-suited for the synthesis of fluorinated biaryls and complex heterocyclic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: