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Structure of 502496-21-1
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This bench-stable hydrazine derivative features a fluorinated aryl ring paired with a trifluoromethyl group, enabling efficient coupling in C–N bond formation. The hydrochloride salt enhances solubility and handling, streamlining use in synthetic routes for pharmaceutical intermediates and functional materials.
(4-Fluoro-2-(trifluoromethyl)phenyl)hydrazine hydrochloride serves as a versatile building block for constructing heterocyclic scaffolds, particularly in the synthesis of pyrazoles and triazoles via cyclization reactions. Its hydrazine functionality enables reliable coupling with carbonyl compounds and electrophilic partners under mild conditions, offering excellent functional group tolerance and bench stability. The molecule’s trifluoromethyl and fluorine substituents enhance metabolic stability and modulate electronic properties, making it valuable for medicinal chemistry applications requiring precise tuning of physicochemical profiles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: