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(S)-3-((tert-Butoxycarbonyl)amino)-3-(naphthalen-1-yl)propanoic acid

  • CAS No. 500770-68-3

  • Cat. No. CS-0179094
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-3-((tert-Butoxycarbonyl)amino)-3-(naphthalen-1-yl)propanoic acid|CS-0179094

Structure of 500770-68-3

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General Information

  • CAS No. 500770-68-3
  • Cat. No. CS-0179094
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₂₁NO₄
  • Molecular Weight 315.36
  • Synonym(s) BOC-(S)-3-AMINO-3-(1-NAPHTHYL)-PROPIONIC ACID
  • SMILES CC(C)(OC(N[C@H](C1=CC=CC2=CC=CC=C21)CC(O)=O)=O)C

Description

(S)-3-((tert-Butoxycarbonyl)amino)-3-(naphthalen-1-yl)propanoic acid is a chiral building block featuring a protected amino group and a naphthyl moiety. This scaffold integrates a sterically hindered, bench-stable α-amino acid unit with a planar aromatic system, enabling direct incorporation into peptide conjugates and bioactive molecule synthesis under standard conditions.

Application

(S)-3-((tert-Butoxycarbonyl)amino)-3-(naphthalen-1-yl)propanoic acid serves as a valuable chiral building block for the synthesis of biologically relevant scaffolds. The protected α-amino acid functionality enables efficient coupling reactions and subsequent deprotection under standard conditions. Its naphthyl moiety provides structural rigidity and π-conjugation, enhancing its utility in medicinal chemistry applications. Bench-stable and readily purified by chromatography, it functions effectively in peptide-like sequences and heterocyclic ring formations.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   3.8803
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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