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CS-W001157 4
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(S)-2-Amino-2-cyclobutylacetic acid

  • CAS No. 49607-08-1

  • Cat. No. CS-W021160
  • Purity≥97%
  • MDL No.MFCD08436202

*For research and further manufacturing use only, not for direct human use.

(S)-2-Amino-2-cyclobutylacetic acid|CS-W021160

Structure of 49607-08-1

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General Information

  • CAS No. 49607-08-1
  • Cat. No. CS-W021160
  • Purity ≥97%
  • MDL No. MFCD08436202
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁NO₂
  • Molecular Weight 129.16
  • Synonym(s) N-cyclobutylglycine
  • SMILES O=C(O)[C@@H](N)C1CCC1

Description

(S)-2-Amino-2-cyclobutylacetic acid features a chiral cyclobutyl group that imparts distinct stereochemical control in peptide synthesis. This bench-stable amino acid derivative integrates readily into peptidomimetics, offering enhanced conformational rigidity and metabolic stability. The cyclobutyl moiety provides unique steric and electronic properties beneficial for targeting bioactive conformations in drug discovery.

Application

(S)-2-Amino-2-cyclobutylacetic acid serves as a valuable chiral building block for the synthesis of bioactive molecules, particularly in medicinal chemistry and peptide-based drug discovery. Its cyclobutyl substituent imparts distinct conformational rigidity, enabling precise control over molecular geometry. The molecule exhibits excellent bench stability, facilitates straightforward purification, and demonstrates compatibility with standard amino acid coupling protocols. Functions as a key scaffold in the development of targeted therapeutics.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   0.1984
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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