Lot numbers can be found on the outside label of a product:
Boc-L-cyclobutylglycine
-
CAS No. 155905-77-4
- Cat. No. CS-W021157
- Purity≥97%
- MDL No.MFCD06659975
*For research and further manufacturing use only, not for direct human use.
Structure of 155905-77-4
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 155905-77-4
- Cat. No. CS-W021157
- Purity ≥97%
- MDL No. MFCD06659975
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₁H₁₉NO₄
- Molecular Weight 229.27
- Synonym(s) None
- SMILES O=C(O)[C@@H](NC(OC(C)(C)C)=O)C1CCC1
Description
Boc-L-cyclobutylglycine features a cyclobutyl ring fused to a glycine backbone, delivering enhanced conformational rigidity for peptide backbone stabilization. This sterically constrained scaffold improves metabolic stability and modulates bioavailability in peptidomimetic design. The Boc protecting group enables straightforward incorporation into solid-phase synthesis workflows under standard conditions.
Application
Boc-L-cyclobutylglycine serves as a valuable building block in peptide synthesis, offering a rigid cyclobutyl side chain that modulates conformational flexibility and enhances metabolic stability. Its Boc group provides reliable protection for the amine functionality, enabling straightforward deprotection under mild acidic conditions. The compound exhibits excellent bench stability, facilitates efficient purification, and demonstrates broad compatibility in standard coupling protocols, making it well-suited for the construction of bioactive peptides and cyclic scaffolds.
Synthesis
-
Route1
-
116611-45-1 - ~%
-
In-stock
155905-77-4
References
-
Tetrahedron Letters, , vol. 35, # 2 p. 237 - 240
-
-
Route2
-
155905-73-0
- ~%
-
In-stock
155905-77-4
References
-
Tetrahedron Letters, , vol. 35, # 2 p. 237 - 240
-
-
Route3
-
116611-45-1
-
109-70-6
- ~%
-
In-stock
155905-77-4
References
-
Tetrahedron Letters, , vol. 35, # 2 p. 237 - 240
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 75.63
- LogP 1.7644
- H_Acceptors 3
- H_Donors 2
- Rotatable_Bonds 3
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Boc-L-cyclobutylglycine sigmaBoc-L-cyclobutylglycine manufacturerBoc-L-cyclobutylglycine priceBoc-L-cyclobutylglycine structureBoc-L-cyclobutylglycine SDSbuy Boc-L-cyclobutylglycineBoc-L-cyclobutylglycine supplierBoc-L-cyclobutylglycine usesBoc-L-cyclobutylglycine molecular weightprice of Boc-L-cyclobutylglycineBoc-L-cyclobutylglycine chemical name formula of Boc-L-cyclobutylglycine