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CS-W001157 4
Total: USD 88.00

2,3-Dihydrobenzo[b][1,4]dioxine

  • CAS No. 493-09-4

  • Cat. No. CS-W017762
  • Purity≥98%
  • MDL No.MFCD00006821

*For research and further manufacturing use only, not for direct human use.

2,3-Dihydrobenzo[b][1,4]dioxine|CS-W017762

Structure of 493-09-4

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General Information

  • CAS No. 493-09-4
  • Cat. No. CS-W017762
  • Purity ≥98%
  • MDL No. MFCD00006821
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈O₂
  • Molecular Weight 136.15
  • Synonym(s) 2,3-Dihydro-1,4-benzodioxine
  • SMILES C1COC2=C(O1)C=CC=C2

Description

The anti-inflammamtory properties and synthesis of carboxylic acid compounds containing benzo-1,4-dioxane (2,3-dihydro-1,4-benzodioxin) subunit was studied.Benzo-1,4-dioxane (2,3-dihydro-1,4-benzodioxin) was used in the synthesis of stereoisomers which were evaluated as - and - adrenergic antagonists.

Synthesis

  • Route1
    • 2-(2-Bromophenoxy)ethan-1-ol|CS-0217600
      34743-89-0
    • ~86%
    • In-stock
      2,3-Dihydrobenzo[b][1,4]dioxine|CS-W017762
      493-09-4

    References

    • Toracca, Karen E.; Kuwabe, Shin-Itsu; Buchwald, Stephen L. Journal of the American Chemical Society, 2000 , vol. 122, # 51 p. 12907 - 12908
  • Route2
    • null|null
      120-80-9
    • null|null
      106-93-4
    • ~87%
    • In-stock
      2,3-Dihydrobenzo[b][1,4]dioxine|CS-W017762
      493-09-4

    References

    • Lyushin, M.M.; Bakus, Yalda Pimanos; Budzema, Khamada Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , p. 832 - 833 Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 8 p. 1040 - 1041
  • Route3
    • null|null
      67470-89-7
    • ~%
    • In-stock
      2,3-Dihydrobenzo[b][1,4]dioxine|CS-W017762
      493-09-4

    References

    • Coudert, Gerard; Ayerbe, Nathalie; Lepiere, Franck; Routier, Sylvain; Caignard, Daniel-Henri; Renard, Pierre; Hickman, John; Pierre, Alain; Leonce, Stephane Patent: US2006/40930 A1, 2006 ; Location in patent: Page/Page column 9 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H412
Precautionary Statements : P210-P264-P273-P280-P302+P352-P362+P364-P370+P378-P403-P501

Quality Control

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   1.4578
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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