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CS-W001157 4
Total: USD 88.00

Dihydrobenzopyran

  • CAS No. 493-08-3

  • Cat. No. CS-M3130
  • Purity≥98%
  • MDL No.MFCD00138123

*For research and further manufacturing use only, not for direct human use.

Dihydrobenzopyran|CS-M3130

Structure of 493-08-3

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General Information

  • CAS No. 493-08-3
  • Cat. No. CS-M3130
  • Purity ≥98%
  • MDL No. MFCD00138123
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O
  • Molecular Weight None
  • Synonym(s) Chroman; Chromane
  • SMILES C12=CC=CC=C1CCCO2

Description

Dihydrobenzopyran serves as a core scaffold in natural product synthesis and pharmaceutical development. This oxygenated heterocycle features a fused benzene and dihydropyran ring system, offering a rigid yet functional platform for derivatization. The molecule exhibits favorable solubility and stability under standard conditions, enabling straightforward incorporation into complex molecular architectures.

Application

Dihydrobenzopyran serves as a versatile scaffold in synthetic organic chemistry, enabling access to functionalized heterocycles through standard oxidation and substitution reactions. Its bench-stable structure facilitates reliable incorporation into complex molecular architectures, particularly in the construction of natural product analogs and pharmaceutical intermediates. Functions as a key building block for pyran-based frameworks with predictable reactivity and favorable purification profiles.

Synthesis

  • Route1

    References

    • BOEHRINGER INGELHEIM INTERNATIONAL GmbH; CARSON, Rebekah J.; FADER, Lee; KAWAI, Stephen; LANDRY, Serge Patent: WO2009/62288 A1, 2009 ; Location in patent: Page/Page column 72-73 ;
  • Route2

    References

    • VERNALIS RESEARCH LIMITED Patent: US2005/187282 A1, 2005 ; Location in patent: Page/Page column 10 ; US 20050187282 A1
  • Route3

    References

    • Niu, Jiajia; Guo, Pengran; Kang, Juntao; Li, Zhigang; Xu, Jingwei; Hu, Shaojing Journal of Organic Chemistry, 2009 , vol. 74, # 14 p. 5075 - 5078

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335-H225
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   2.0116
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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