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CS-W001157 4
Total: USD 88.00

3-Ethoxy-2-hydroxybenzaldehyde

  • CAS No. 492-88-6

  • Cat. No. CS-W017873
  • Purity≥98%
  • MDL No.MFCD00003323

*For research and further manufacturing use only, not for direct human use.

3-Ethoxy-2-hydroxybenzaldehyde|CS-W017873

Structure of 492-88-6

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General Information

  • CAS No. 492-88-6
  • Cat. No. CS-W017873
  • Purity ≥98%
  • MDL No. MFCD00003323
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₃
  • Molecular Weight 166.18
  • Synonym(s) ORTHO-ETHYLVANILLIN
  • SMILES O=CC1=CC=CC(OCC)=C1O

Description

3-Ethoxysalicylaldehyde was used in the preparation of:Schiff base ligand via condensation with trans-1,2-diaminocyclohexanesubstituted salen-type Schiff base ligandsa new Schiff base, 2-ethoxy-6-[(3-methylaminopropylimino)methyl]phenol, via reaction with N-methylpropane-1,3-diamine

Application

3-Ethoxy-2-hydroxybenzaldehyde serves as a versatile ortho-functionalized aromatic building block, enabling efficient access to substituted benzaldehydes and heterocyclic scaffolds. Its hydroxyl and ethoxy groups provide orthogonal reactivity for selective derivatization, while the aldehyde functionality facilitates condensation reactions, including Mannich and Knoevenagel transformations. Bench-stable and amenable to standard purification methods, it supports scalable synthesis in medicinal chemistry and materials development.

Synthesis

  • Route1
    • 3-Ethoxy-2-methoxybenzaldehyde|CS-1672384
      75792-34-6
    • ~83%
    • In-stock
      3-Ethoxy-2-hydroxybenzaldehyde|CS-W017873
      492-88-6

    References

    • Chemistry Letters, , # 7 p. 738 - 739
  • Route2

    References

    • Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 42, # SUPPL. 1 p. S723-S725
  • Route3
    • null|null
      15950-66-0
    • ~%
    • In-stock
      3-Ethoxy-2-hydroxybenzaldehyde|CS-W017873
      492-88-6

    References

    • US6034256 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.6034
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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