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CS-W001157 4
Total: USD 88.00

2-Ethoxyphenol

  • CAS No. 94-71-3

  • Cat. No. CS-0040351
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Ethoxyphenol|CS-0040351

Structure of 94-71-3

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General Information

  • CAS No. 94-71-3
  • Cat. No. CS-0040351
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀O₂
  • Molecular Weight 138.16
  • Synonym(s) Guaethol; Guethol; NSC 180
  • SMILES OC1=CC=CC=C1OCC

Description

2-Ethoxyphenol is a smoke flavour compound and forms complexes with iron (III).2-Ethoxyphenol has been used as carbon and energy supplement in the growth medium of red-pigmented coryneform bacterium, Rhodococcus rhodochrous strain 116.

Application

2-Ethoxyphenol serves as a versatile building block in synthetic organic chemistry, enabling the construction of bioactive heterocycles and pharmaceutical intermediates. Its phenolic functionality offers predictable reactivity in electrophilic substitution and coupling reactions, while the ethoxy group provides moderate stability and ease of purification. The molecule functions effectively in standard derivatization protocols, including Suzuki-Miyaura and Ullmann couplings, and exhibits favorable handling characteristics for bench-scale synthesis.

Synthesis

  • Route1
    • 2-Ethoxycyclohexan-1-one|CS-0332852
      33371-97-0
    • ~%
    • In-stock
      2-Ethoxyphenol|CS-0040351
      94-71-3

    References

    • US3992452 A1, ;
  • Route2
    • null|null
      120-80-9
    • null|null
      75-03-6
    • ~67%
    • In-stock
      2-Ethoxyphenol|CS-0040351
      94-71-3

    References

    • Simon Fraser University; The University of British Columbia Patent: US2010/160451 A1, 2010 ; Location in patent: Page/Page column 9 ;
  • Route3
    • null|null
      64-67-5
    • null|null
      120-80-9
    • ~76%
    • In-stock
      2-Ethoxyphenol|CS-0040351
      94-71-3

    References

    • Xu, Maoyou; Zhang, Jin; Wu, Xue; Sun, Juanjuan; Shi, Zhiqiang Synthetic Communications, 2010 , vol. 40, # 7 p. 992 - 997

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H302-H315-H318-H335
Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   1.7909
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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