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CS-W001157 4
Total: USD 88.00

Quipazine

  • CAS No. 4774-24-7

  • Cat. No. CS-0072166
  • Purity≥95%
  • MDL No.MFCD00242605

*For research and further manufacturing use only, not for direct human use.

Quipazine|CS-0072166

Structure of 4774-24-7

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General Information

  • CAS No. 4774-24-7
  • Cat. No. CS-0072166
  • Purity ≥95%
  • MDL No. MFCD00242605
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₅N₃
  • Molecular Weight 213.28
  • Synonym(s) None
  • SMILES C1(N2CCNCC2)=NC3=CC=CC=C3C=C1

Description

Quipazine is a substituted indole derivative featuring a quinazoline core, engineered for high stability under ambient conditions. This compound integrates readily into medicinal chemistry campaigns targeting serotonin receptor modulation, offering predictable reactivity and ease of purification.

Application

Quipazine serves as a versatile scaffold for medicinal chemistry exploration, particularly in the synthesis of serotonin receptor modulators. Its indole core enables straightforward functionalization and compatibility with standard coupling reactions. The molecule exhibits bench stability and facilitates efficient derivatization under mild conditions, supporting rapid analog generation for target engagement studies.

Synthesis

  • Route1
    • null|null
      110-85-0
    • In-stock
      2-Chloroquinoline|CS-W007458
      612-62-4
    • ~99%
    • In-stock
      Quipazine|CS-0072166
      4774-24-7

    References

    • Asagarasu, Akira; Matsui, Teruaki; Hayashi, Hiroyuki; Tamaoki, Satoru; Yamauchi, Yukinao; Minato, Kouichi; Sato, Michitaka Journal of Medicinal Chemistry, 2010 , vol. 53, # 21 p. 7549 - 7563
  • Route2
    • null|null
      112036-71-2
    • ~82%
    • In-stock
      Quipazine|CS-0072166
      4774-24-7

    References

    • Jensen, Jorgen A.; Pedersen, Erik B. Archiv der Pharmazie (Weinheim, Germany), 1987 , vol. 320, # 10 p. 1088 - 1092
  • Route3
    • null|null
      103-84-4
    • ~%
    • In-stock
      Quipazine|CS-0072166
      4774-24-7

    References

    • Jensen, Jorgen A.; Pedersen, Erik B. Archiv der Pharmazie (Weinheim, Germany), 1987 , vol. 320, # 10 p. 1088 - 1092

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   28.16
  • LogP   1.6444
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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