(R)-3-Methoxypyrrolidine hydrochloride

Name: (R)-3-Methoxypyrrolidine hydrochloride
Brand: ChemScene
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CAS No. 474707-30-7
Cat. No. CS-W021134
Purity≥95%
MDL No.MFCD11849816

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(R)-3-Methoxypyrrolidine hydrochloride|CS-W021134

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General Information

CAS No. 474707-30-7
Cat. No. CS-W021134
Purity ≥95%
MDL No. MFCD11849816
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₂ClNO
Molecular Weight 137.61
Synonym(s) (R)-3-METHOXY-PYRROLIDINE HYDROCHLORIDE
SMILES CO[C@H]1CNCC1.[H]Cl

Description

(R)-3-Methoxypyrrolidine hydrochloride is a stereochemically defined heterocyclic amine featuring a methoxy group at the 3-position, offering enhanced solubility and stability under standard conditions. This bench-stable compound serves as a key chiral building block in medicinal chemistry, enabling efficient access to bioactive molecules through direct incorporation into complex scaffolds.

Application

(R)-3-Methoxypyrrolidine hydrochloride serves as a stereochemically defined heterocyclic building block for medicinal chemistry and catalytic synthesis. The pyrrolidine core provides a rigid, nitrogen-containing scaffold with enhanced solubility and metabolic stability. The methoxy group offers a handle for further functionalization, while the hydrochloride salt ensures excellent bench stability, ease of handling, and compatibility with standard purification protocols. This compound enables efficient access to chiral amine intermediates in API development.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 21.26
LogP 0.4165
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Key Words

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(R)-3-Methoxypyrrolidine hydrochloride

CAS No. 474707-30-7

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