(3S,4S)-Pyrrolidine-3,4-diol

Name: (3S,4S)-Pyrrolidine-3,4-diol
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 90481-32-6
Cat. No. CS-W005107
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 90481-32-6

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 90481-32-6
Cat. No. CS-W005107
Purity ≥97%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₉NO₂
Molecular Weight 103.12
Synonym(s) 1,4-dideoxy-1,4-iminothreitol
SMILES O[C@H]1CNC[C@@H]1O

Description

This chiral pyrrolidine diol features a rigid, fused 3,4-diol framework with defined (3S,4S) stereochemistry, enabling precise control in asymmetric synthesis. The hydroxyl groups facilitate hydrogen bonding and enhance solubility in polar solvents, while the stable scaffold resists racemization under standard conditions.

Application

(3S,4S)-Pyrrolidine-3,4-diol serves as a stereochemically defined scaffold for the synthesis of bioactive heterocycles and natural product analogs. Its rigid, cis-diols enable predictable stereocontrol in downstream transformations, while the pyrrolidine core offers favorable solubility and metabolic stability. The compound functions effectively in nucleophilic additions, cyclizations, and as a chiral building block in medicinal chemistry campaigns requiring precise spatial orientation. Bench-stable and readily purified by standard chromatographic methods, it supports scalable synthesis workflows.

Synthesis

Route1
- In-stock
  
  90365-74-5
- ~97%
- In-stock
  
  90481-32-6
References
- Hui, Ailing; Zhang, Jintang; Wang, Zhiyong Synthetic Communications, 2008 , vol. 38, # 14 p. 2374 - 2384
Route2
- 1428671-12-8
- ~%
- In-stock
  
  90481-32-6
References
- Bioorganic and Medicinal Chemistry, , vol. 21, # 7 p. 1911 - 1917

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 52.49
LogP -1.6886
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Key Words

(3S,4S)-Pyrrolidine-3,4-diol sigma(3S,4S)-Pyrrolidine-3,4-diol manufacturer(3S,4S)-Pyrrolidine-3,4-diol price(3S,4S)-Pyrrolidine-3,4-diol structure(3S,4S)-Pyrrolidine-3,4-diol SDSbuy (3S,4S)-Pyrrolidine-3,4-diol(3S,4S)-Pyrrolidine-3,4-diol supplier(3S,4S)-Pyrrolidine-3,4-diol uses(3S,4S)-Pyrrolidine-3,4-diol molecular weightprice of (3S,4S)-Pyrrolidine-3,4-diol(3S,4S)-Pyrrolidine-3,4-diol chemical name formula of (3S,4S)-Pyrrolidine-3,4-diol

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(3S,4S)-Pyrrolidine-3,4-diol

CAS No. 90481-32-6

Recommended Products