Boc-Tyr(tBu)-OH

Name: Boc-Tyr(tBu)-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 47375-34-8
Cat. No. CS-W011915
Purity≥98%
MDL No.MFCD00065598

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 47375-34-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 47375-34-8
Cat. No. CS-W011915
Purity ≥98%
MDL No. MFCD00065598
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₈H₂₇NO₅
Molecular Weight 337.41
Synonym(s) None
SMILES O=C(O)[C@H](CC1=CC=C(OC(C)(C)C)C=C1)NC(OC(C)(C)C)=O

Description

Boc-Tyr(tBu)-OH is a protected tyrosine derivative featuring a tert-butyl carbamate (Boc) group at the N-terminus and a tert-butyl ester on the phenolic hydroxyl. This dual protection enables stable incorporation into peptide chains under standard coupling conditions, offering enhanced solubility and resistance to premature deprotection during synthetic sequences.

Application

Boc-Tyr(tBu)-OH serves as a protected tyrosine building block for peptide synthesis, offering stable handling and compatibility with standard coupling protocols. The Boc group enables selective deprotection under mild acidic conditions, while the tert-butyl ester preserves phenolic hydroxyl reactivity for downstream modifications. Its robustness facilitates purification and integration into complex sequences without side reactions.

Synthesis

Route1
- 24424-95-1
- 4727-00-8
- ~76%
- In-stock
  
  47375-34-8
References
- Atherton, Eric; Caviezel, Mario; Fox, Hazel; Harkiss, Diana; Over, Hilary; Sheppard, Robert C. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 1 p. 65 - 73

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 84.86
LogP 3.3843
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 5

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Tyrosine and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

Key Words

Boc-Tyr(tBu)-OH sigmaBoc-Tyr(tBu)-OH manufacturerBoc-Tyr(tBu)-OH priceBoc-Tyr(tBu)-OH structureBoc-Tyr(tBu)-OH SDSbuy Boc-Tyr(tBu)-OHBoc-Tyr(tBu)-OH supplierBoc-Tyr(tBu)-OH usesBoc-Tyr(tBu)-OH molecular weightprice of Boc-Tyr(tBu)-OHBoc-Tyr(tBu)-OH chemical name formula of Boc-Tyr(tBu)-OH

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Boc-Tyr(tBu)-OH

CAS No. 47375-34-8

Recommended Products