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CS-W001157 4
Total: USD 88.00

(5-Fluorobenzofuran-2-yl)boronic acid

  • CAS No. 473416-33-0

  • Cat. No. CS-W007009
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(5-Fluorobenzofuran-2-yl)boronic acid|CS-W007009

Structure of 473416-33-0

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General Information

  • CAS No. 473416-33-0
  • Cat. No. CS-W007009
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BFO₃
  • Molecular Weight 179.94
  • Synonym(s) Boronic acid, (5-fluoro-2-benzofuranyl)- (9CI)
  • SMILES FC1=CC=C(OC(B(O)O)=C2)C2=C1

Description

This boronate moiety integrates readily into Suzuki-Miyaura couplings, delivering functionalized fluoroaryl scaffolds with high efficiency. The electron-deficient aryl ring enhances reactivity while maintaining bench-stable handling under standard conditions.

Application

(5-Fluorobenzofuran-2-yl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation with aryl halides and triflates. Its stability under ambient conditions and compatibility with diverse functional groups facilitate straightforward incorporation into complex molecular architectures. The fluorinated benzofuran scaffold provides enhanced metabolic stability and tunable electronic properties, making it a valuable component in the synthesis of bioactive molecules and pharmaceutical intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   53.6
  • LogP   0.2517
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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