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CS-W001157 4
Total: USD 88.00

(3-Methylpyridin-4-yl)boronic acid

  • CAS No. 894808-72-1

  • Cat. No. CS-W018785
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3-Methylpyridin-4-yl)boronic acid|CS-W018785

Structure of 894808-72-1

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General Information

  • CAS No. 894808-72-1
  • Cat. No. CS-W018785
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈BNO₂
  • Molecular Weight 136.94
  • Synonym(s) boronic acid, B-(3-methyl-4-pyridinyl)-
  • SMILES CC1=C(C=CN=C1)B(O)O

Description

(3-Methylpyridin-4-yl)boronic acid features a pyridine ring bearing both a methyl group and a boronic acid moiety, enabling direct incorporation into Suzuki-Miyaura cross-coupling reactions. The electron-deficient heterocycle enhances reactivity, while the ortho-methyl substituent provides steric control and improved stability under standard conditions.

Application

(3-Methylpyridin-4-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation with aryl and heteroaryl halides. Its pyridyl boronate functionality offers good bench stability, moderate functional group tolerance, and facilitates straightforward purification via crystallization or chromatography. Widely used in medicinal chemistry and agrochemical synthesis, it functions as a key scaffold component for constructing biologically active heterocycles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   -0.93018
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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