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Boronic acid, B-(5-bromo-2-benzofuranyl)-

  • CAS No. 331833-99-9

  • Cat. No. CS-0029510
  • Purity≥98%
  • MDL No.MFCD06801726

*For research and further manufacturing use only, not for direct human use.

Boronic acid, B-(5-bromo-2-benzofuranyl)-|CS-0029510

Structure of 331833-99-9

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General Information

  • CAS No. 331833-99-9
  • Cat. No. CS-0029510
  • Purity ≥98%
  • MDL No. MFCD06801726
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BBrO₃
  • Molecular Weight 240.85
  • Synonym(s) 5-bromobenzofuran-3-ylboronic acid
  • SMILES BrC1=CC=C(OC(B(O)O)=C2)C2=C1

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, delivering biaryl architectures with high functional group tolerance. The brominated heterocyclic scaffold enhances reactivity and stability in synthetic workflows.

Application

(5-Bromobenzofuran-2-yl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its stability, ease of handling, and compatibility with diverse functional groups make it ideal for constructing complex heterocyclic architectures in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Friedman; Toyne; Goodby; Hird Journal of Materials Chemistry, 2001 , vol. 11, # 11 p. 2759 - 2772
  • Route2
    • null|null
      106-41-2
    • ~%
    • In-stock
      Boronic acid, B-(5-bromo-2-benzofuranyl)-|CS-0029510
      331833-99-9

    References

    • Friedman; Toyne; Goodby; Hird Journal of Materials Chemistry, 2001 , vol. 11, # 11 p. 2759 - 2772
  • Route3
    • 1-Bromo-4-(2,2-dimethoxyethoxy)benzene|CS-0334541
      129969-69-3
    • ~%
    • In-stock
      Boronic acid, B-(5-bromo-2-benzofuranyl)-|CS-0029510
      331833-99-9

    References

    • Friedman; Toyne; Goodby; Hird Journal of Materials Chemistry, 2001 , vol. 11, # 11 p. 2759 - 2772

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   53.6
  • LogP   0.8751
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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