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Structure of 470482-44-1
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This pyrrolidine derivative features a tert-butoxycarbonyl-protected amine and a sterically demanding trifluoromethyl group at the 4-position, enhancing stability and modulating electronic properties. The chiral scaffold supports stereoselective synthesis in peptide mimetics and medicinal chemistry applications.
(2S,4R)-1-(tert-Butoxycarbonyl)-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid serves as a stereochemically defined building block for the synthesis of bioactive pyrrolidine-containing scaffolds. The tert-butoxycarbonyl (Boc) group enables convenient protection and deprotection under mild acidic conditions, while the trifluoromethyl substituent imparts enhanced metabolic stability and modulates lipophilicity. This compound facilitates efficient coupling reactions and functions as a key intermediate in the construction of peptidomimetics and heterocyclic drug candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: