Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(2S,4R)-1-(tert-Butoxycarbonyl)-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid

  • CAS No. 470482-44-1

  • Cat. No. CS-0053422
  • Purity≥97%
  • MDL No.MFCD08458253

*For research and further manufacturing use only, not for direct human use.

(2S,4R)-1-(tert-Butoxycarbonyl)-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid|CS-0053422

Structure of 470482-44-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 470482-44-1
  • Cat. No. CS-0053422
  • Purity ≥97%
  • MDL No. MFCD08458253
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆F₃NO₄
  • Molecular Weight 283.24
  • Synonym(s) (2S,4R)-1-Boc-4-trifluoromethylpyrrolidine-2-carboxylic acid
  • SMILES CC(C)(C)OC(=O)N1C[C@@H](C[C@H]1C(O)=O)C(F)(F)F

Description

This pyrrolidine derivative features a tert-butoxycarbonyl-protected amine and a sterically demanding trifluoromethyl group at the 4-position, enhancing stability and modulating electronic properties. The chiral scaffold supports stereoselective synthesis in peptide mimetics and medicinal chemistry applications.

Application

(2S,4R)-1-(tert-Butoxycarbonyl)-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid serves as a stereochemically defined building block for the synthesis of bioactive pyrrolidine-containing scaffolds. The tert-butoxycarbonyl (Boc) group enables convenient protection and deprotection under mild acidic conditions, while the trifluoromethyl substituent imparts enhanced metabolic stability and modulates lipophilicity. This compound facilitates efficient coupling reactions and functions as a key intermediate in the construction of peptidomimetics and heterocyclic drug candidates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   66.84
  • LogP   2.2589
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 470482-44-1 sigma470482-44-1 manufacturer470482-44-1 price470482-44-1 structure470482-44-1 SDSbuy 470482-44-1470482-44-1 supplier470482-44-1 uses470482-44-1 molecular weightprice of 470482-44-1470482-44-1 chemical name formula of 470482-44-1
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label