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CS-W001157 4
Total: USD 88.00

Azido-PEG1-amine

  • CAS No. 464190-91-8

  • Cat. No. CS-0114595
  • Purity≥95%
  • MDL No.MFCD23726611

*For research and further manufacturing use only, not for direct human use.

Azido-PEG1-amine|CS-0114595

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General Information

  • CAS No. 464190-91-8
  • Cat. No. CS-0114595
  • Purity ≥95%
  • MDL No. MFCD23726611
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀N₄O
  • Molecular Weight 130.15
  • Synonym(s) None
  • SMILES [N-]=[N+]=NCCOCCN

Description

Azido-PEG1-amine features a reactive azide group linked to a short PEG spacer and primary amine terminus, enabling efficient bioorthogonal conjugation via click chemistry. This bifunctional scaffold supports site-specific labeling and immobilization in peptide, protein, and oligonucleotide modifications under mild conditions.

Application

Azido-PEG1-amine serves as a versatile bifunctional linker for bioconjugation and polymer functionalization. The azide group enables efficient copper-catalyzed (CuAAC) or strain-promoted (SPAAC) click reactions, while the primary amine facilitates coupling with activated esters or aldehydes. Its short PEG spacer provides solubility and reduced steric hindrance, enhancing reactivity in peptide and oligonucleotide modifications. Ideal for modular synthesis of drug conjugates and surface-functionalized materials.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H305-H315-H317-H319
Precautionary Statements : P261-P264-P270-P272-P280-P301+P310-P302+P352-P305+P351+P338-P330-P331-P332+P313-P333+P313-P337+P313-P362+P364-P363-P405-P501

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Computational Chemistry Data

  • TPSA   84.01
  • LogP   0.272
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   5

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