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CS-W001157 4
Total: USD 88.00

(1-Azabicyclo[2.2.2]oct-4-yl)(diphenyl)methanol

  • CAS No. 461648-39-5

  • Cat. No. CS-M1579
  • Purity≥98%
  • MDL No.MFCD22665854

*For research and further manufacturing use only, not for direct human use.

(1-Azabicyclo[2.2.2]oct-4-yl)(diphenyl)methanol|CS-M1579

Structure of 461648-39-5

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General Information

  • CAS No. 461648-39-5
  • Cat. No. CS-M1579
  • Purity ≥98%
  • MDL No. MFCD22665854
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₂₃NO
  • Molecular Weight 293.40
  • Synonym(s) Diphenyl(quinuclidin-4-yl)methanol
  • SMILES OC(C1=CC=CC=C1)(C2=CC=CC=C2)C34CCN(CC4)CC3

Synthesis

  • Route1
    • In-stock
      Ethyl quinuclidine-4-carboxylate|CS-M1578
      22766-68-3
    • null|null
      591-51-5
    • ~61%
    • In-stock
      (1-Azabicyclo[2.2.2]oct-4-yl)(diphenyl)methanol|CS-M1579
      461648-39-5

    References

    • Laine, Dramane I.; McCleland, Brent; Thomas, Sonia; Neipp, Christopher; Underwood, Brian; Dufour, Jeremy; Widdowson, Katherine L.; Palovich, Michael R.; Blaney, Frank E.; Foley, James J.; Webb, Edward F.; Luttmann, Mark A.; Burman, Miriam; Belmonte, Kristen; Salmon, Michael Journal of Medicinal Chemistry, 2009 , vol. 52, # 8 p. 2493 - 2505
  • Route2
    • In-stock
      Ethyl 1-(2-chloroethyl)piperidine-4-carboxylate|CS-M1972
      869112-14-1
    • null|null
      591-51-5
    • ~55%
    • In-stock
      (1-Azabicyclo[2.2.2]oct-4-yl)(diphenyl)methanol|CS-M1579
      461648-39-5

    References

    • GLAXO GROUP LIMITED; HOSSNER, Frank; STRACHAN, John Bryce Patent: WO2014/27045 A1, 2014 ; Location in patent: Page/Page column 10 ;
  • Route3
    • In-stock
      4-Carboethoxypiperidine|CS-W009052
      1126-09-6
    • null|null
      591-51-5
    • null|null
      540-51-2
    • ~53%
    • In-stock
      (1-Azabicyclo[2.2.2]oct-4-yl)(diphenyl)methanol|CS-M1579
      461648-39-5

    References

    • GLAXO GROUP LIMITED; HOSSNER, Frank; STRACHAN, John Bryce Patent: WO2014/27045 A1, 2014 ; Location in patent: Page/Page column 10; 11 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   23.47
  • LogP   3.4084
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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