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CS-W001157 4
Total: USD 88.00

4-Carboethoxypiperidine

  • CAS No. 1126-09-6

  • Cat. No. CS-W009052
  • Purity≥97%
  • MDL No.MFCD00006003

*For research and further manufacturing use only, not for direct human use.

4-Carboethoxypiperidine|CS-W009052

Structure of 1126-09-6

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General Information

  • CAS No. 1126-09-6
  • Cat. No. CS-W009052
  • Purity ≥97%
  • MDL No. MFCD00006003
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₅NO₂
  • Molecular Weight 157.21
  • Synonym(s) Ethyl isonipecotate; NSC 93792; Piperidin-4-carboxylic acid ethyl ester; Isonipecotic Acid Ethyl Ester
  • SMILES O=C(C1CCNCC1)OCC

Description

Hydroxy-PEG2-methyl ester is a PEG linker containing a hydroxyl group and a methyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Methyl ester can be hydrolyzed under strong basic condition.

Synthesis

  • Route1
    • Piperidine-4-carboxylic acid Avatrombopag Impurity|CS-0377512
      498-94-2
    • null|null
      64-17-5
    • ~94%
    • In-stock
      4-Carboethoxypiperidine|CS-W009052
      1126-09-6

    References

    • Nguyen, William; Howard, Brittany L.; Jenkins, David P.; Wulff, Heike; Thompson, Philip E.; Manallack, David T. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 23 p. 7106 - 7109
  • Route2

    References

    • Journal of Organic Chemistry, , vol. 17, p. 249,254 Helvetica Chimica Acta, , vol. 37, p. 1672,1676
  • Route3
    • null|null
      1083159-13-0
    • ~%
    • In-stock
      4-Carboethoxypiperidine|CS-W009052
      1126-09-6

    References

    • Organic Letters, , vol. 10, # 22 p. 5155 - 5158

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   0.5491
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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