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CS-W001157 4
Total: USD 88.00

cis-3,5-Dimethylmorpholine

  • CAS No. 45597-00-0

  • Cat. No. CS-0057260
  • Molecule weight115.17
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

cis-3,5-Dimethylmorpholine|CS-0057260

Structure of 45597-00-0

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General Information

  • CAS No. 45597-00-0
  • Cat. No. CS-0057260
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO
  • Molecular Weight 115.17
  • Synonym(s) (3R,5S)-3,5-Dimethylmorpholine
  • SMILES C[C@H]1COC[C@@H](C)N1

Description

cis-3,5-Dimethylmorpholine is a sterically hindered, bench-stable nitrogen heterocycle featuring two methyl groups at the 3- and 5-positions of the morpholine ring. This configuration enhances conformational rigidity and modulates basicity, enabling selective reactivity in synthetic transformations. The molecule's electron-rich character facilitates nucleophilic participation in catalytic processes and serves as a tunable scaffold for medicinal chemistry applications.

Application

cis-3,5-Dimethylmorpholine serves as a stable, bench-friendly nitrogen heterocycle enabling efficient access to diverse scaffolds in medicinal chemistry. Its constrained conformation enhances metabolic stability and modulates physicochemical properties. The molecule reacts predictably with electrophiles and functions effectively as a building block for targeted functionalization, offering high compatibility in standard coupling and derivatization protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   0.3832
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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