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Structure of 46032-98-8
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This chiral diol features a rigid, stereodefined scaffold with adjacent hydroxyl and amino groups, enabling precise molecular recognition. The (1R,2R) configuration ensures high enantioselectivity in asymmetric synthesis. The phenyl ring enhances π-stacking potential, while the polar functional groups support hydrogen bonding in catalytic systems. This compound serves as a key building block for bioactive molecules and ligands.
(1R,2R)-2-Amino-1-phenylpropane-1,3-diol serves as a chiral synthon for the construction of bioactive heterocycles and amino acid derivatives. Its three contiguous functional groups—primary amine, secondary alcohol, and benzylic alcohol—enable selective derivatization and protection strategies in peptide and natural product synthesis. Bench-stable and readily purified by recrystallization, it functions as a key building block in asymmetric synthesis workflows requiring stereocontrolled access to vicinal amino-alcohol motifs.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: