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CS-W001157 4
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(S)-1-Fluoropropan-2-amine hydrochloride

  • CAS No. 458560-63-9

  • Cat. No. CS-0090252
  • Molecule weight113.56
  • Purity≥95%
  • MDL No.MFCD22196467

*For research and further manufacturing use only, not for direct human use.

(S)-1-Fluoropropan-2-amine hydrochloride|CS-0090252

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General Information

  • CAS No. 458560-63-9
  • Cat. No. CS-0090252
  • Purity ≥95%
  • MDL No. MFCD22196467
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₉ClFN
  • Molecular Weight 113.56
  • Synonym(s) (S)-1-Fluoro-2-propylamine Hydrochloride
  • SMILES C[C@H](N)CF.[H]Cl

Description

(S)-1-Fluoropropan-2-amine hydrochloride is a chiral fluorinated amine featuring a stereodefined secondary amine center and a fluoro substituent at the alpha position. This bench-stable, moisture-tolerant reagent integrates readily into asymmetric synthesis workflows, enabling direct incorporation of fluorinated motifs into bioactive scaffolds with high stereocontrol.

Application

(S)-1-Fluoropropan-2-amine hydrochloride serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of fluorinated bioactive molecules. Its well-defined stereochemistry and bench-stable form facilitate straightforward incorporation into peptide-like scaffolds and heterocyclic systems. The compound exhibits favorable functional group tolerance and reacts efficiently in standard amine coupling and alkylation protocols, supporting scalable synthesis and purification workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P233-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   0.7249
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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